"Hooper's Hope" is a film that presents a view of the world from the perspective of germs. The agents of infectious disease would like nothing better than for humans to be mired in a free-for-all of conflict and mistrust. By ignoring advances in public health science and the advice of dedicated public health scientists, we are at risk of returning to the heyday of infectious diseases. This is exactly what Hooper, a whooping cough bacteria, hopes happens. Fanning the flames of mistrust is an inferno of misinformation and disinformation on the internet. This Hooper's Hope channel offers a short animated film as a satirical look at this problem, but also offers references to scientific papers and suggestions for how we might prevent sliding into a very serious Public Health crisis.